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KMID : 1149120210180020029
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Journal of the Korean Society for Psoriasis
2021 Volume.18 No. 2 p.29 ~ p.35
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Evaluation of Treatment Satisfaction after Treatment with Biologics in Patients with Moderate to Severe Psoriasis
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Shim Dong-Hyun
Kim Min-Sung
Na Chan-Ho
Choi Hoon
Shin Bong-Seok
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Abstract
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Background: Psoriasis is a chronic disease, which is linked on significant negative impact on patients’ quality of life (QoL). Although the high efficacy of biologics in psoriasis has been well known through objective measures, studies on their treatment satisfaction are limited.
Objective: To evaluate treatment satisfaction for patients with psoriasis treated with biologics who have experience in oral agent treatment.
Methods: Treatment satisfaction was evaluated at the time of treatment with oral agents before administration of the biologics and at the last visit after administration of the biologics. QoL was evaluated by Dermatology Life Quality Index (DLQI) and treatment satisfaction was evaluated by Treatment Satisfaction Questionnaire for Medication (TSQM)-9.
Results: Treatment satisfaction with biologics was higher in all effectiveness, convenience, and global satisfaction domains compared to when treated with oral agents (p<0.001), and the mean score ranged from 73.8 to 80.1.The difference in treatment satisfaction score was not significant depending on the type of biologic being administered, and the better the treatment response after administration to the biologic, the higher the treatment satisfaction was, which showed a statistically significant correlation (p<0.05). DLQI score significantly decreased from 22.2± 5.2 to 3.1±3.3 after biologics treatment (p<0.001).
Conclusion: The results of this study showed that biologics improved treatment satisfaction and QoL in psoriasis patients. Evaluation of treatment satisfaction will be helpful in comparing various medications and making treatment decisions.
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KEYWORD
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Biologics, Psoriasis, Satisfaction, TSQM
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